A Survey of Human Disease Gene Counterparts in the Drosophila Genome

نویسندگان

  • Mark E. Fortini
  • Marian P. Skupski
  • Mark S. Boguski
  • Iswar K. Hariharan
چکیده

A Survey of Human Disease Gene Counterparts in the Drosophila Genome Mark E. Fortini,* Marian P. Skupski, ‡ Mark S. Boguski, § and Iswar K. Hariharan i *Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104; ‡ Celera Genomics, Rockville, Maryland 20850; § National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland 20894; and i Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts 02129

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

I-49: Human Y Chromosome ProteomeProject

The success of the Human Genome Project (HGP) has provided a blueprint for the approximately 20,000 gene-encoded proteins potentially active in all of the hundreds of cell types that make up the human body. Yet we still have limited knowledge about a majority of the gene-encoded proteins which are the “building blocks of life” and “cellular machinery”. It is estimated that for nearly half of th...

متن کامل

Survey of Coronaviruses Infection among Patients with Flu-like Symptoms in the Golestan Province, Iran

ABSTRACT             Background and objectives: Coronaviruses are the main causes of respiratory tract infections in humans. They are also the second leading cause of common cold after rhinoviruses, and can lead to otitis media and asthma. The aim of this study was to investigate the molecular detection of coronaviruses in clinical samples of patients with flu-like symptoms.             Metho...

متن کامل

Genome-wide computational prediction of miRNAs in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) revealed target genes involved in pulmonary vasculature and antiviral innate immunity

The current outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)in China threatened humankind worldwide. The coronaviruses contains the largest RNA genome among all other known RNA viruses, therefore the disease etiology can be understood by analyzing the genome sequence of SARS-CoV-2. In this study, we used an ab-intio based computational tool VMir to scan the complete geno...

متن کامل

بررسی بیان ژن lnT هلیکوباکتر پیلوری در سلول‌های HDF انسان به روش RT-PCR

Background and Objectives: Helicobacter pylori is a gram-negative and spiral bacterium that causes stomach and duodenal disease in humans. Because of the presence of disadvantages in antibiotic therapies, increasing efforts  have been made to produce effective vaccine for this infection. The aim of this study was to generate a construct   carrying the lnT gene and to survey its...

متن کامل

Molecular detection of proteolytic activity of human parechovirus 2A protein by gene expression

  Parechoviruses form one of the nine genera in the picornaviridae family, and include two human pathogens: Human parechovirus type1 and 2 (Hpev1 and Hpev2). The genome of picornaviruses encodes a single polyprotein, which undergoes a cleavage cascade performed by virus encoded proteases to give the final virus proteins. The primary cleavage occurs by 2A protein and this step is critical for vi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Journal of Cell Biology

دوره 150  شماره 

صفحات  -

تاریخ انتشار 2000